Other Autoimmune Diseases

There are over 80 recognized autoimmune diseases. Major categories are characterized by genetic association to MHC Class II and to antigens that activate autoreactive T cells via binding to disease-associated alleles.

Provid has ongoing projects directed toward inhibitors of DR1 and DR4, associated with rheumatoid arthritis and other diseases and toward DQ2 and DQ8, associated with celiac disease and type 1 diabetes. The MHC strategy is a platform technology that Provid can pursue for multiple disease categories.

Autoimmune diseases